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Philly's Annual Vendor Show June 2022

posted Apr 3, 2022, 2:01 PM by Jean Husten   [ updated May 19, 2022, 9:03 AM by Rodney Bednar ]

https://www.eventbrite.com/e/lrig-philadelphia-annual-vendor-show-2022-tickets-313094031677
Thursday June 16, 2022  (4:00 PM to 8:00 PM) 
Philly LRIG Annual Vendor Exhibition 

the Alloy King of Prussia - a DoubleTree by Hilton- Valley Forge
King of Prussia, PA 19406 

Google Map Direction



Vendor Exhibition:  4:00 PM to 8:00 PM
Novel Technologies Presentations:  5:00 PM to 8:00 PM
Free Food: (4:30-7:00) & Desert (6:00 to 8:00)
Prizes Sponsored by SLAS

Overview

Free food, networking, vendors/exhibitors, great talks

The LRIG Philadelphia Annual Vendor Exhibition is scheduled for Thursday June 16th 2022 and will be held at the Alloy King of Prussia - a DoubleTree by Hilton- Valley Forge from 4:00pm to 8:00 pm. This Technology Exhibition will showcase the latest in laboratory instrumentation, automation, software, reagents and consumables. Free food will be served and the meeting will provide a wonderful networking opportunity for area scientists and engineers to connect and share ideas

Click Links in "Contents" (see below) for Quick Access to Details

Menu

Free delicious food served during the event




Novel Technology Presentations

A break out room will host short (15 min)  presentations focusing on new state-of-the art technologies throughout the evening.
Click Here to See Novel Technology Abstracts

2022 Novel Technology Presentations

4:30

How automation helped increase workflow efficiency during the peak of COVID testing

Presented by: Phillip Darden – Sales Specialist, Laboratory Products – Hamilton Storage

4:50

Novel Sample Collection Technologies iSWAB-MB-EL and NextSWAB Increase the Efficiency of SARS-CoV-2 Testing by Bypassing RNA Extraction Steps

Presented by: Ayah El-Fahmawi, Mawi DNA Technologies LLC (in conjunction with diaago)

5:10

Scaling Beyond COVID Rapid Testing

Presented by: Chuck Adams, Sales Director –Eastern North America, BioDot Inc.

5:30

Control Under Pressure

Presented by: Josh Lamontage, Product Manager, Festo Corporation

5:50

Improve Your Assay Automation Workflow with New QualAssure™ Solutions from Artel

Presented by:  Dr. Melinda Gold, Applications Specialist, Artel

6:10

Enable More Quality Critical Attribute (QCA) Workflows

Presented by: Kenda LJ Evans, PhD, Automation Product Specialist, Agilent Technologies

6:30

Getting the Most From your Automated Liquid Handler: Leveraging Open Sourced Robotics In Laboratory Workflows

Presented by: Kathryn Liles, Manager FAS Team, Opentrons Labworks

6:50

Orchestrating Your Discoveries Beyond the Integrated Workstation

Presented by: Casey Fowler, Field Application Scientist, Biosero

7:10

How to adopt an Automation-First Mentality

Presented by: Steven Watters, North America Sales Manager, HighRes Biosolutions


Novel Technology Abstracts

How automation helped increase workflow efficiency during the peak of COVID testing

Presented by:  Phillip Darden – Sales Specialist, Laboratory Products – Hamilton Storage

When the COVID-19 pandemic started, accurate testing became a top priority for countries around the world. As testing ramped up, labs suddenly faced an exponential increase to their usual number of samples to process. Unfortunately, many of these labs were lagging due to manually intensive practices. Over the course of the pandemic, however, the testing response time improved tremendously thanks to the power of automation.  

Hamilton Storage’s line of cappers and decappers allows labs to increase throughput while reducing the risk of cross-contamination. Manually capping and recapping tubes is time-intensive and has the potential to create a bottleneck in the lab because there are physical limits to how many samples can be processed. It can take a person more than 10 minutes to decap 96 tubes, while it takes the LabElite DeCapper less than 60 seconds. By automating the entire workflow, cross-contamination is virtually eliminated. Naturally, this leads to increased sample safety and fewer false positives. 

As of May 2, 2022, the United States had performed nearly 1 billion tests for COVID-19–the highest number of any country worldwide. Thanks in large part to automated benchtop devices such as the LabElite DeCapper, an overwhelming majority of these tests were deemed reliable and the results helped curb further spread of the virus.

Novel Sample Collection Technologies iSWAB-MB-EL and NextSWAB Increase the Efficiency of SARS-CoV-2 Testing by Bypassing RNA Extraction Steps

Presented by: Ayah El-Fahmawi, Mawi DNA Technologies LLC (in conjunction with diaago)

Viral testing via qPCR is one of the most effective tools in pandemic control. The onset of the COVID-19 Pandemic and emergence of the Delta variant created supply chain pressures and labor shortages that contributed to major lab backlogs, compromising sample integrity and the ability to conduct large-scale testing necessary for effective pandemic responses. To combat these challenges, Mawi DNA Technologies released two novel sample collection technologies: iSWAB®-MB-EL and the NextSWAB. iSWAB®-MB-EL is an Extraction-Less sample collection solution designed to eliminate RNA extraction from COVID-19 molecular testing workflows, allowing researchers to perform direct RT-PCR on COVID samples. Bypassing time-sensitive and delicate RNA extraction steps allows labs to deliver results sooner, increase testing throughput, and reduce costs. iSWAB®-MB-EL has been validated for use with several COVID-19 EUA Molecular diagnostic tests, including traditional RT-qPCR and rapid detection RT-LAMP based methods. The iSWAB®-MB-EL solution inactivates COVID-19 and stabilizes samples at ambient temperature for at least 28 days, eliminating the need for expensive cold-chain transport. In response to swab shortages, Mawi also released the NextSWAB, a sterile, 100% injection-molded plastic applicator designed for the high-efficiency collection and release of nasal samples. The flexible head is designed with two channels separated by a septum to retain the collected nasal material until the user releases it into transport media with a gentle shake. Eliminating absorbent material allows for effective release and concentration of the specimen. The NextSWAB is a comfortable, high-performing traditional swab alternative that offers multifunctional use for sample collection without the possibility of contamination from glue or fibers used in flocked and cotton swabs. All Mawi products including iSWAB-MB-EL and NextSWAB are manufactured in the US to reduce supply chain risks.

Scaling Beyond COVID Rapid Testing

Presented by: Chuck Adams, Sales Director –Eastern North America, BioDot Inc.

COVID is still a testing challenge for citizens, businesses, and entire countries. The pandemic afforded us (the healthcare community) the opportunity to improve processes, and most importantly to advance science. The regulatory process has streamlined approvals for testing, both in the tests used and in the labs that can perform the tests, but due the magnitude of testing, simplification and economics in testing became key drivers, and this is where rapid test technology shines. Point-of-Care (POC) Over the Counter (OTC) tests are now approved for COVID and there will be more to follow, likely in other infectious disease areas. Beyond COVID, we see a medicine cabinet filled with home tests for Influenza, Streptococcus, Pneumonia, all connected via mobile devices to your physician via telemedicine. If results are negative, only then do you proceed to Urgent Care. The applications reach far beyond infectious disease - think about food allergies. How many of us have nut, dairy, gluten or seafood allergies? When venturing out to a restaurant and verifying with the server that the food is allergy-free, would we not want to have our own portable rapid test in hand to verify that it actually is a gluten-free dish before we indulge? The point here is COVID was the door opener to simplified, affordable testing which puts the testing device in the hands of the patient and consumer. The next step is to consider how to develop these rapid tests and how these tests can be produced at scale. That is where BioDot comes in. BioDot made its mark in this industry in 1994 with patented, non-contact, nanoliter (nL) dispensing technology and then designed instrumentation to precisely dispense volumes onto a variety of surfaces. A rapid test is typically either a lateral flow test or a biochip/biosensor device. The surfaces used in lateral flow are porous and dispensing is best done without touching (disrupting) the material (non-contact). Conversely, in biochip/biosensor applications, the surfaces are often rigid plastic wells, but they require absolute placement of many different low-volumes of liquids (>36 different types) to be dispensed simultaneously and quickly. Both examples stated (lateral flow and biochip/biosensor) benefit from BioDot’s non-contact, nanoliter dispensing technology. As with most science, development of a rapid test begins with research, progresses to prototyping, and ultimately advances to production volumes once a test has been proven and is ready for sale. BioDot has a product offering to suit the needs of our customers with entry-level R&D platforms that scale as their development and production needs get defined. Our R&D systems are used to produce batches of up to 500,000 rapid tests per year. As our customer’s tests gain market adoption, with volumes greater than 1M tests per year, migrating to our high production instrumentation for printing and lamination is common. If your group has ELISA/antigen/antibody expertise and are considering a rapid test development effort, this presentation will further expand on the trends in this space and make recommendations of how to avoid pitfalls in your “rapid test” quest.

Control Under Pressure

Presented by: Josh Lamontage, Product Manager, Festo Corporation

Using pneumatic technology to build high performance liquid dispensing systems. One of the central topics in laboratory automation is the handling of the smallest amounts of liquid – from milliliters to nanoliters. This requires not only absolute precision but also maximum flexibility, because the most diverse media and changing fluid properties place special demands on the solutions used. Pressure-controlled liquid dosing systems are a simple and efficient way to achieve precision, scalable liquid handling. This presentation conveys the constructive basics of such dispensing systems – including the control of flow, pressure, and other variables to optimize the throughput. In addition, selected systems, and products from Festo, which are presented in these solutions are used.

Improve Your Assay Automation Workflow with New QualAssure™ Solutions from Artel

Presented by:  Dr. Melinda Gold, Applications Specialist, Artel

Different liquids have different properties, and depending on their viscosity, density, volatility, etc., that can introduce challenges with your liquid handler delivery volumes and ultimately with your assay. Parameters can be adjusted in your automated liquid handler to ensure the accuracy and precision of the volumes being dispensed, but DIY methods are time-consuming. Therefore, Artel has added two additional solutions to the existing QualAssure portfolio so you don’t have to operate blindly and waste expensive assay reagents. As assay throughput increases, the limit of detection decreases, and assay volumes decrease there is a general higher level of scrutiny on quality. Automation addresses many of these issues and is becoming more prevalent than ever before. However, developing liquid classes can be a complex and arduous process. PCR master mix and serum are two common non-ideal solutions used in a variety of essential assays. Due to the unique rheological properties of these solutions, compounded by the absolute need for accurate and precise results of these assays, scientists depend on liquid handling precision and accuracy. In many cases, scientists optimize their liquid class settings with the actual reagents or biological solutions, however, this is problematic due to prohibitive cost, rarity, or resource requirements.  Simply using water or a glycerol mixture to mimic these solutions is not a suitable option since there are additional liquid class parameters that need to be taken into consideration. It is possible to reliably measure and adjust for master mix like liquids as well as various serums by using the new PCRMix™ and SerumSub™ QualAssure solutions. These solutions have liquid handling properties analogous to commonly used PCR master mixes and sera, respectively, and are used to help improve automated assay workflows.

Enable More Quality Critical Attribute (QCA) Workflows

Presented by: Kenda LJ Evans, PhD, Automation Product Specialist, Agilent Technologies

The AssayMAP Bravo is a flexible yet easy-to-use automated protein sample preparation platform. The system leverages microchromatography and preoptimized applications to perform a wide variety of protein sample preparation workflows required during biotherapeutic development. We have made several advances that allow the AssayMAP Bravo to address even more of the drug development process. The system can now use large capacity packed resin bed cartridges allowing for more sample to be processed for downstream analysis as well as quicker time to results while maintaining reproducibility and low elution volumes.

Getting the Most From your Automated Liquid Handler: Leveraging Open Sourced Robotics In Laboratory Workflows

Presented by: Kathryn Liles, Manager FAS Team, Opentrons Labworks

Many automation systems are completely closed when it comes to software licenses and any modifications you want to make to the system. Users rely on expensive services or void warranties if they do want their own integrations. Our open source philosophy transcends our software to enable our community of users to take complete control of their automation systems and leverage our expertise and resources along the way. We offer free, downloadable software, a host of plug and play scripts in our protocol library and have a SA to help with custom integrations.

Orchestrating Your Discoveries Beyond the Integrated Workstation

Presented by: Casey Fowler, Field Application Scientist, Biosero

Meeting today’s demands to accelerate the pace of scientific discoveries and get life-enhancing products to the market sooner, a critical need for increasing process efficiency and digital connectivity within the laboratory has arisen. A solution beyond the integrated workstation is vital to this need. Biosero is partnering with laboratories to orchestrate the flow of physical and digital materials across entire end-to-end laboratory workflows. Our solution goes beyond the integrated workstation, capturing and contextualizing data at every point along the laboratory automation continuum. Join us as we explore strategies for digitalizing manual tasks, governing stand-alone instruments, and controlling fully automated workstations while integrating new and legacy data systems.

How to adopt an Automation-First Mentality

Presented by: Steven Watters, North America Sales Manager, HighRes Biosolutions

Successful laboratory automation requires us to think in the language of automation rather than thinking about traditional workflows or related terms first (i.e., increasing throughput using the current methodology), which invariably add project risk when automation principles are applied afterward. For example, many scientists are introduced to automation through automated liquid handling devices. However, liquid handlers are highly specialized themselves, and adding multiple other specialized devices to a liquid handling deck ensures that the deck’s size will physically constrain both the amount and extent of the hands-free work that can be performed on it. More importantly, this approach to laboratory automation may limit the very range of possible solutions that we can conceive. Simply put, how we allow ourselves to think about how we conduct science determines how we are able to think about science itself. For laboratory automation to keep pace with science, concepts such as that of the modular workflow must be taken “off deck”. This allow new paradigms to emerge – ones that incorporate laboratory devices, samples distribution and software to reimagine total workflows and data use. Only in this way can laboratory automation truly adapt and re-adapt to inevitable changes in one’s science, technology, or organization. In this talk, we explore an “automation-first” journey into laboratory automation to expand the capabilities of hands-free science.

LIST of 2022 Exhibiting Vendors and HYPERLINKS

Detailed Vendor Info

Agilent Cell Analysis

Agilent is growing in the cell analysis space. What started as a unique offering of solutions focused on understanding cellular functionality based on underlying metabolic programming has transformed into a market-leading set of innovative tools with the additions of ACEA Biosciences and BioTek Instruments – providing customers the tools they need to uncover unique cell biology, discover novel drug targets, improve preclinical in vitro toxicology, and pioneer the next generation of immunotherapies.

Agilent Technologies

Agilent is a global leader in life science, diagnostics and analytical laboratory technologies. Leveraging more than 50 years of expertise, we create instruments, software, services and solutions that provide trusted answers to our customers’ most critical questions. We are passionate about helping them solve their most ambitious scientific challenges, increase laboratory performance, and advance the quality of life.

Analytik Jena

Analytik Jena offers with its liquid handling systems a perfect solution for daily pipetting routines. With Analytik Jena solutions you increase the efficiency of your processes – from compact liquid handling systems for daily pipetting routines up to automated simultaneous pipettors all the way to robotic systems tailored to your application, throughput, and capacity requirements.

Araceli Biosciences

Araceli Biosciences is a novel high content screening company. Our goal is to disrupt the status quo of drug discovery by blending advanced hardware platforms with AI-powered analytics

ArcticWhite

ArcticWhite offers a family of products for laboratory efforts in high throughput screening, compound storage, ADME, drug metabolism, pharmacokinetics, targeted compound synthesis, drug discovery, PCR, and gene expression. As research, scientific, and medical laboratory equipment suppliers, we offer the best materials needed for day-to-day research. Our lab supplies list features a full range of multi-well plates, sample concentrators, sample management instrumentation, heat sealers, custom coatings for both cell based and enzyme based assays, and the ArctiSeal™ brand of sealing mat closures, ArcticWhite can meet all of your lab equipment and supply needs.

Arrayjet

Arrayjet microarrayers are built-to-order and completely scalable, from R&D to commercial array manufacture. An industrial-grade print head ensures precision and consistency, and twin QC cameras work with the intuitive software to evaluate printing in real-time, automatically reprinting any missing spots.
Arrayjet Advance is our CRO element. Customers can outsource their custom array printing projects to an experienced team using advanced technology. We can spot high-density microarrays of any biological sample or small molecule compound libraries, and a dedicated Lead Scientist will consult with you throughout.

Artel

Artel helps its customers ensure the quality of their laboratory test results. Our products and services enable quick, easy optimization of liquid handling processes for automated liquid handlers and handheld pipettes. The MVS (Multichannel Verification System) allows you to verify accuracy and precision, troubleshoot, and optimize the performance of your automated liquid handlers and multichannel pipettes. Artel Liquid Handling Service combines the superior volume measurement capabilities of the MVS with the expertise of an Artel Field Service Technician in your lab to increase productivity and confidence in assay results by removing liquid handling as a source of error in your processes.

Avidien Technologies

We are a Massachusetts based company specializing in precision liquid handling products. Our mission is to create innovative solutions that simplify the jobs of researchers and lab technicians. Quality, simplicity and precision are the foundation for everything we make.

axiVEND

axiVEND provides liquid dispensing systems from M2-Automation to spot microarrays or load biosensors (pin-based contact and non-contact piezo- and solenoid-based), as well as from Lets Go Robotics, to quickly and accurately fill microtiter plates with 80 nl to 2 ml reagent or cell suspension volumes. We supply iRiS Kinetics label-free readers for the easy measurement of biomolecular affinities, as well as microarray readers, both colorimetric and fluorometric. We offer services for the spotting of microarrays or biochips, as well as cartridge assembly under ISO 13485, and for the measurement of binding kinetics. We are located in Orlando, Florida.

Azenta Life Sciences

Azenta provides a full suite of automated sample stores, consumables, instruments, and reliable cold-chain sample management solutions and genomic services across areas such as drug development, clinical research and advanced cell therapies for the industry's top pharmaceutical, biotech, academic and healthcare institutions globally.

Beckman Coulter Life Sciences

Beckman Coulter is dedicated to advancing and optimizing the laboratory. For over 80 years, we’ve advanced scientific research and patient care. Our focus on innovation, reliability and efficiency has made us the partner of choice for clinical, research and industrial customers globally. In the life sciences, researchers use our precision instruments to study complex biological problems, including causes of disease and potential new treatments. We have over 270,000 systems in universities, government, biotechnology and pharmaceutical companies, hospitals, and commercial laboratories. At Beckman Coulter, we’re challenging conventional wisdom; our goal is to develop the best, most widely trusted laboratory solutions available.

BioDot

Printing Smaller, Faster, Smarter… For over 25 years, BioDot has focused on precision low volume (picoliter to nanoliter) dispensing systems for R&D and manufacturing in the life science, diagnostic and medical product markets. With over 5000 systems placed around the world and 27 global patents we are committed to providing leading edge technologies in assay miniaturization, high density plate filling, microfluidics, biosensors, NGS, custom applications, etc.

BioNex Solutions, Inc.

BioNex Solution’s leading edge automation innovations have led to strategic alliances with leading companies in the pharmaceutical, agricultural, biotech and diagnostic industries. Our mission is to innovate for current and future automated applications for the advancement in life science discovery and expanded healthcare to the benefit of humankind.

Biosero

Biosero, a member of the BICO group, develops science-centric software and laboratory automation tools that enable researchers to orchestrate their discoveries at every stage. Our Green Button Go software and integration services match laboratory automation to your science, creating a cohesive technology ecosystem that accelerates operations and increases productivity. On its own, Green Button Go software is an end-to-end laboratory management solution, orchestrating workflows and procedures in life science, biotechnology, pharmaceutical, and diagnostic research.

BlueCatBio

Since winning SLAS and MipTec new product awards in 2015, the centrifugal Blue®Washer has become the new standard for non-contact media removal used by most top 25 pharma companies. Blue®Washer uses centrifugation to remove liquids from 96, 384 and 1536w plates, eliminating background and variability from assay data. For cellular assays, Blue®Washer’s reproducible, low residual volumes < 0.3 µl/ well raise z' by 0.1-0.3, delivering more meaningful compound profiles to chemists. For magnetic bead assays such as AMPure® bead clean-up in NGS library preparation, Blue®Washer dramatically reduces run time and tip waste.

BMG Labtech

BMG LABTECH is a German-based company that focuses exclusively on microplate readers and our technological innovations have made us a leader in the field. We offer a wide range of dedicated and multi-mode microplate readers for life sciences applications and high-throughput screening.

DCM BioServices

At DCM BioServices we know that you want to be a leader in laboratory research, testing and manufacturing. In order to do that, you need your work to continue unimpeded, without the headache and stress of unexpected downtime. The problem is you have laboratory equipment that needs to maintenance, repair, set up or more and you're worried about the costs and how long it will take to get back up and running. We believe that your investment in laboratory automation equipment should last and lighten your workload. Come talk to us about how you can eliminate downtime with DCM BioServices.

diaago

diaago is a team of dedicated, experienced professionals who understand and care about your research needs and success. With experience in laboratory operations, manufacturing, international supply chain, and best practices, we provide next-level insight and support. We offer a carefully curated selection of laboratory equipment, consumables, support services, and other resources to the research community. Our focus is on quality and consistency, so you can focus on results.

Dynamic Devices

Dynamic Devices’ Volume Verified Pipetting independently controls each channel in 8, 24 or 96 pipette tools by precise real time monitoring, enabling automatic error detection and correction. The measured pressure differential across an integrated restriction also allows for independent volume per channel, full pipette data tracking, as well as air-in-sample and clog detection for all samples, regardless of the physical properties of the liquid or requirement to pre-generate liquid class characterizations.

Enzo Life Sciences

Enzo Life Sciences, Inc. is a recognized leader in labeling and detection technologies across research and diagnostic markets. Our strong portfolio of proteins, antibodies, peptides, small molecules, labeling probes dyes and kits provides life science researchers tools for target identification/validation,  high content analysis,  gene expression analysis, nucleic acid detection, protein biochemistry and detection, and cellular analysis. As Scientists Enabling Healthcare, Enzo realizes the value in providing relevant application data to our customers in the Life Science and Drug Discovery markets.

Festo Corporation

For 50 years in the US Festo has been a positive force for manufacturers. Our passion is automation - creating intelligent automation solutions that transform the way people work, the way companies compete. Ultimately, it’s about continuously stimulating progress. Our aim is to help our customers make their products faster, smarter and more precise. Rather than surviving, they can thrive as industry leaders. And when our customers win, we win.

Frontier Scientific

Frontier Scientific’s core competency of Outsourced Materials Management and Sample Preparation Services supports multi-industry Compound Management, R&D Screening and Chemistry groups. Frontier performs sample reformatting and full management and repository services with on-demand distribution of client building blocks or screening samples, featuring 24-72 hour global delivery.  Frontier offers pre-weighed intermediates and building blocks, stock solution creation, uL or nL plating and reformatting, high throughput analysis and procurement services.

Grenova

Grenova develops and implements solutions to wash plastic consumables in life science laboratories for reuse. Learn how your lab can reduce plastic waste, save on consumables, and mitigate supply-chain volatility.

Hamilton Company

For over 60 years, trust has been the hallmark of every precision-crafted solution at Hamilton Company. Private, public, and academic institutions across the globe and throughout diverse scientific and clinical reams trust in Hamilton’s ergonomic manual precision measurement devices and powerful automated liquid handling workstations to streamline cumbersome workflows and aid in answering complex questions. Assay-ready workstations are depended upon to fully automate sample preparation, drug of abuse testing, toxicology, pain management testing, next-generation sequencing (NGS), ELISA, and many other workflows for enhanced efficiency and reproducibility.

Hamilton Storage

Hamilton Storage, an affiliate entity of Hamilton Company, is a global leader in the design and manufacturing of automated storage systems for biological and compound samples. By safeguarding the integrity of even the most precious samples, our solutions and expert knowledge empower researchers to reach new heights of laboratory efficiency while remaining focused on life science research. Our sample storage solutions, benchtop devices, and consumables are designed for sample integrity, flexibility, and reliability for life science applications. Hamilton Storage continues to develop innovative technologies to fit market needs and be known as the sample care company for the life science industry.

HighRes BioSolutions

HighRes believes in a future where scientists and robots work together. As the technology leader in lab automation, we believe in a future where scientists and robots collaborate to discover new solutions, faster than ever before.  Our laboratory automation systems and devices provide you with the ability to scale and reconfigure automation systems as technologies change. These systems let scientists focus on what they do best, driving discoveries and improving human health. Our commitment to robust product design, rigorous process controls, continuous improvement, and teamwork is how we take you there.

INTEGRA Biosciences

INTEGRA is a leading provider of high-quality laboratory tools and consumables for liquid handling and media preparation. We are committed to fulfilling the needs of laboratory professionals in research, diagnostics, and quality control within the life sciences industry.

JG Finneran Porvair

JG Finneran, a leading USA manufacturer, together with Kbiosystems and Porvair Sciences, offer over 40 years of experience in manufacturing, designing, and engineering sample prep consumables and equipment. Our robust product range includes blowdown evaporators, plate sealers, colony pickers, plate handlers, barcode applicators, microplates and related accessories, including sealing films and cap mats. Offering OEM customer platforms, custom designs, as well as installation.

Mettler Toledo

METTLER TOLEDO is a leading global manufacturer of precision instruments. The Company is the world’s largest manufacturer and marketer of weighing instruments for use in laboratory, industrial and food retailing applications. The Company also holds top-three market positions in several related analytical instruments markets and is a leading provider of automated chemistry systems used in drug and chemical compound discovery and development. Additional information about METTLER TOLEDO can be found at www.mt.com/lab.

Opentrons Labworks

We are an open source, life science company with a mission to democratize lab automation. We offer an affordable, scalable, and modular system that is capable of both complex and simple liquid handling tasks with limitless possibilities due to the open-source nature. We have an unprecedented support team to make sure our users get up and running quickly and have the resources to develop protocols as the needs of the lab change.

PerkinElmer

PerkinElmer, Inc. is a global leader committed to innovating for a healthier world. Our optimized, automated solutions are designed to improve the efficiency of genomic and proteomic workflows. With our proprietary nucleic acid isolation technology, flexible liquid handlers, robust library preparation solutions, automated nucleic acid analysis and protein characterization systems, and innovative solutions for single cell genetic analysis, PerkinElmer is eliminating the challenges associated with genomic and proteomic analysis.

Sirius Automation

Sirius Automation: Machines for Routines®. General purpose & Tailored (Custom) Benchtop Laboratory Robotics for sample preparation etc. For such routine tasks as Analytical Weighing; Sample ID (1D/2D barcodes), Liquid + Slurry handling, Solids Dosing, Sorting, Dilutions, Vortex, Tumble or ultrasonic mixing, Disc Filtration, Vial Filtration, Internal Standard Addition, Standard Prep, Un-Capping & Re-Capping, Transfers & Aliquoting using YOUR CHOICE of labware. Incorporates 21CFR11 & GLP Compliance Capabilities. Multiple Platform choices. Automate not Populate.

Tecan

Tecan is a leading global provider of automated liquid handlers and microplate readers & washers. Our systems help people working in clinical diagnostics, basic & translational research, and drug discovery bring their science to life. In under four decades Tecan has grown from a Swiss family business to a brand that is well established on the global stage of life sciences. From pioneering days on a farm to the leading role our business assumes today – empowering research, diagnostics and many applied markets around the world.

Thermo Scientific Laboratory Products

Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving complex analytical challenges, improving patient diagnostics and therapies or increasing productivity in their laboratories, we are here to support them.

Worldwide Glass Resources

Worldwide Glass Resources® is a premier solution provider offering engineering and technical expertise in the design and production of laboratory and packaging vials. Our range of products include Standard and Custom High Recovery Vials for Purification and Compound Storage Libraries, Autosampler vials, Headspace vials, Sample Vials, Limited Volume Inserts, septa lined aluminum seals and closures, etc. A full array of services is offered including bar-coding (ceramic and polyolefin), tare & weighing, and custom vial manufacturing including, MS vial certifications, and Vial-Armor™ deactivation.

Ziath

Ziath specializes in instrumentation control and information management in both the academic and the pharmaceutical/biotech industry sectors with a focus on the application of laboratory automation. In particular, we focus on managing large sample libraries (compound management, biobanking and sample management) using 2D Datamatrix tubes


Vendor Booth Layout

LRIG Philadelphia 8th Virtual Scientific Meeting

posted Jul 3, 2021, 8:56 AM by Rodney Bednar   [ updated Aug 6, 2021, 8:30 AM by Jackson Hyde ]


On-Demand Viewing of Event Recording is available for a limited time on LRIG's YouTube Channel.  


For Direct Video Link:  https://youtu.be/r6KpFJqieTY




The 8th Virtual Scientific Meeting is Wednesday, July 7th @ NOON! 
 


Please encourage your friends and colleagues to register now for this exciting talk.


Register Now on Eventbrite

LRIG-Philadelphia's Virtual Scientific Meetings provide an opportunity for Scientists to share their research with the LRIG Community.

Join us Wednesday, July 7th @ NOON!  Spend your lunchtime with us learning about the scientific application of mixed reality technology from Elliot Drake, Mixed Reality Digital Technology Specialist at GlaxoSmithKline in Collegeville, PA. 

Free Registration Here

 

Overview of Presentation:

Applications of Mixed Reality Technology for Remote Collaboration and Scientific Training

Due to new-found remote working requirements and social distancing guidelines, GSK has been required to innovate on how it proceeds with global business practices. In this presentation, we will discuss several of the new digital technologies we used to overcome these challenges, and the use cases involved.

 


   LRIG-Philadelphia Virtual Scientific Meeting July 2021 image

Elliot Drake

Elliot Drake is a Mixed Reality Digital Technology Specialist at GlaxoSmithKline in Collegeville, PA. As part of the Analytical Platforms and Platform Modernization group, he and his team support initiatives within the GSK portfolio that focus on digital technology, systems innovation, & business intelligence. His work involves the utilization of Smartglasses, Augmented workflows, Paperless data capture, and AR/VR training modules.

Elliot has direct experience in the fields of Human Computer Interaction, Imaging & 3-D Visualization, Computer graphics, Wearable Technology, Graphical User Interfaces, Internet of Things, and Mixed Reality Training.

LinkedIn: https://linkedin.com/in/ElliotHDrake

Title: Applications of Mixed Reality Technology for Remote Collaboration and Scientific Training

Elliot Drake , GlaxoSmithKline, Collegeville, PA

Abstract: Our first use case involves using Smartglasses technology for an “I See What You See” method that allows users to troubleshoot, train, method-transfer, and audit remotely between sites and both internal and external users. The use of Smartglasses can reduce travel frequencies to different internal sites and external CROs, especially during Covid-19, to troubleshoot and work as a training aid through streaming and video recording, which promotes effective and efficient decision making to meet project timelines.

The second use case involves a direct collaboration with our Vaccines group. Using a group of Virtual Reality training modules to assist with the training of new scientists on following safe procedures when working with HPLC & Lab automation instruments. This is completed with a combination of pre-built and bespoke virtual training modules.

Once the various applications are set up, they reduce time required for traveling or on-site business needs for scientists across different business units. Saving time, resources, capital, and focusing on keeping our scientists safe.

Click Here For Tickets

Help spread the word out about this new forum for Scientists to share their Research and Innovations with the entire LRIG community.   All Laboratory Research and Innovation Group of Philadelphia (LRIG-Philadelphia) events are free and open to all.

If you are interested in presenting or organizing a future event, please send your proposal to Talks.PHL@lrig.org.

Thank you, we'll "see you" on July 7th

Register Now

LRIG Philadelphia 7th Virtual Scientific Meeting

posted Apr 15, 2021, 8:38 AM by Rodney Bednar   [ updated Jul 3, 2021, 9:04 AM ]


https://www.youtube.com/channel/UCI4hxTqKyOwpCnGCxMRulWA

On-Demand Viewing of Event Recording is available for a limited time on LRIG's YouTube Channel.  






For Direct Video Link:


1st Presentation: "Advances in Sonication for MultiOmics Applications with PIXUL" 

Direct Video Link is: https://youtu.be/8Adz_LYaMM8 


2nd Presentation: "Nanoliter Droplet Dispensers for Analytical Mass Spectrometry and other Applications" 

Direct Video Link is: https://youtu.be/otF9GuOr8Yg  




The 7th Virtual Scientific Meeting is Wednesday, May 5th @ NOON!  

Please encourage your friends and colleagues to register now for this exciting talk.

Register Now on Eventbrite

LRIG Philadelphia 6th Virtual Scientific Meeting

posted Apr 3, 2021, 9:08 AM by Rodney Bednar   [ updated Apr 20, 2021, 7:34 PM ]


On-Demand Viewing of Event Recording is available for a limited time on LRIG's YouTube Channel.  


For Direct Video Link:  https://youtu.be/0J2m6RfwDxU





The 6th Virtual Scientific Meeting is Wednesday, April 7th @ NOON!  

Please encourage your friends and colleagues to register now for this exciting talk.

Register Now on Eventbrite


The Laboratory Research & Innovation Group of Philadelphia (LRIG-Philadelphia) is proud to announce our next Virtual Scientific Meeting. This virtual forum provides an opportunity for Scientists to share their Research & Innovations with the entire LRIG Community.  This ongoing series is free to attend and open to all.

About this Event

This lunchtime "WebEx" event will feature Dual Presentations on High Throughput Cellular Thermal Shift by Scientists at NIH/NCATS and at GSK. There will also be an opportunity for questions and answers.

Overview of Presentations:

High Throughput Cellular Thermal Shift Assays (CETSA): Approaches and Applications

During this webinar, high-throughput cellular thermal shift assays (CETSA) will be discussed. CETSA can be used as a method to detect the engagement of a small molecule with a protein target in cells. High throughput methods and applications will be presented.

Please remember to register and join us for this exciting virtual event. The evening before the event you will receive a link that will allow you to join the WebEx meeting.

See below for information on our speakers and an abstract of their presentations.


   LRIG-Philadelphia Virtual Scientific Meeting April 2021 image

Mark Henderson

Dr. Mark Henderson is a Biology Group Leader in the Early Translation Branch at the National Center for Advancing Translational Sciences (NCATS). His team works on collaborative projects aiming to identify small molecules for disease-relevant targets, focusing on cellular processes that are dysregulated across multiple disorders. He has experience in the design, development, and implementation of high throughput screening assays.

LinkedIn: https://www.linkedin.com/in/mark-j-henderson/


   LRIG-Philadelphia Virtual Scientific Meeting April 2021 image

Lorena Kallal, PhD

Lorena Kallal is a scientist and manager at GlaxoSmithKline in Collegeville, PA. As part of the Screening, Profiling and Mechanistic Biology Department, her team supports programs across the GSK portfolio with cellular assays and experimentation. Lorena has expertise in high throughput screening, phenotypic assays, and drug discovery strategy.

LinkedIn: http://www.linkedin.com/in/lorena-kallal-7389a672

Title: High throughput cellular thermal shift assays (CETSA): approaches and applications.

Mark Henderson, National Center for Advancing Translational Sciences (NCATS), NIH & Lorena Kallal , GlaxoSmithKline, Collegeville, PA

Abstract : The cellular thermal shift assay (CETSA) is a valuable method to assess target engagement within the cellular environment by measuring changes in thermal stability of a protein conferred by ligand binding. The traditional CETSA method is labor intensive, which limits its use when testing large sets of compounds during screening or lead optimization. In recent years, several high-throughput CETSA approaches have been developed to overcome this limitation. During this webinar, we will describe high-throughput CETSA approaches and discuss strengths, pitfalls, and potential applications of these technologies.


Register Now on Eventbrite

 

Help spread the word out about this new forum for Scientists to share their Research and Innovations with the entire LRIG community.   All Laboratory Research and Innovation Group of Philadelphia (LRIG-Philadelphia) events are free and open to all.

If you are interested in presenting or organizing a future event, please send your proposal to Talks.PHL@lrig.org.

Thank you, we'll "see you" on April 7th

Register Now on Eventbrite

LRIG Philadelphia 5th Virtual Scientific Meeting

posted Mar 5, 2021, 11:48 AM by Rodney Bednar   [ updated Mar 5, 2021, 11:50 AM ]

https://youtu.be/aB6IAD743L8
On-Demand Viewing of Event Recording is available for a limited time on LRIG's YouTube Channel.  See: 
https://youtu.be/aB6IAD743L8






The 5th Virtual Scientific Meeting is on Wednesday, March 3rd, 2021 @ NOON! 

Please encourage your friends and colleagues to register now for this exciting talk.

REGISTER NOW!


The Laboratory Research & Innovation Group of Philadelphia (LRIG-Philadelphia) is proud to announce our next Virtual Scientific Meeting. This virtual forum provides an opportunity for Scientists to share their Research & Innovations with the entire LRIG Community.  This ongoing series is free to attend and open to all.

About this Event:

   LRIG-Philadelphia Virtual Scientific Meeting March 2021 image

The Laboratory Research & Innovation Group of Philadelphia (LRIG-Philadelphia) and The Pennsylvania Drug Discovery Institute (http://www.padrugdiscovery.org/) is proud to present another Virtual Scientific Meeting. This lunchtime "WebEx" event will feature a presentation by President & CEO of Melior Pharmaceuticals and an opportunity for questions and answers.

Overview of Presentation:

Harnessing Pharmacological Pleiotropy for Drug Repositioning

Although the word “pleiotropy” is customarily used in a genetic sense to refer to the phenomenon where a gene effects multiple traits, here we take the liberty to use it in the sense of a drug having multiple therapeutic actions. We use the biology of lyn kinase, and the activator of lyn kinase, MLR-1023, as an illustrative example.

Please remember to register and join us for this exciting virtual event. The evening before the event you will receive a link that will allow you to join the WebEx meeting.

See below for Information on our speaker and an abstract of his presentation.


   LRIG-Philadelphia Virtual Scientific Meeting March 2021 image

Andrew Reaume

Dr. Reaume is President, CEO and co-founder of Melior Discovery, Inc., an established biopharmaceutical company dedicated to in vivo phenotypic screening and drug repositioning. Under Dr. Reaume’s leadership the Company has advanced from a discovery stage R&D operation to a clinical stage company having completed 2 successful Phase 2 studies involving more than 80 clinical sites across 2 countries. Dr. Reaume has provided instrumental contribution to many key elements of the company’s progress including investment financing, partnership activity for the company’s services, business model architecture and out-licensing of the company’s lead product.

Prior to starting Melior, Dr. Reaume was a Senior Business Analyst at Pfizer Global Research and Development Inc. where, among other activities, he spearheaded a major genomics technology initiative involving impacting all therapeutic areas and involving collaboration with stakeholders throughout the Pfizer global organization. Before Pfizer. he was a Research Scientist in R&D at Cephalon, Inc. where, in addition to R&D activities he became involved in identifying and coordinating in-licensing opportunities. He received his MBA from the Wharton School where he graduated with honors in Entrepreneurial Management. He received his PhD in genetics from the University of Connecticut.

LinkedIn: https://www.linkedin.com/in/andrew-reaume-38b1a72/

Title: Harnessing Pharmacological Pleiotropy for Drug Repositioning

Abstract : Study of the pharmaceutical discovery process, its evolution over the last three or four decades, and its persistent high attrition rate, make it clear that scientific progress has made little or no inroads towards improving new therapeutic entity discovery. A core tenet of this phenomenon is that there is much more that we do not understand about biological systems than the amount that we do understand. We propose that an element of this lack of understanding is the degree to which the therapeutic targets that are modulated by drugs that we work with are involved in more biology, and thereby more therapeutic potential, than most investigators appreciate. This is reflected in the high rate at which drugs are used for indications other than the ones for which they were originally developed. We have coined this phenomenon of multi-therapeutic application for a single drug, pharmacological pleiotropy. MLR-1023, with its activation of lyn kinase, provides an excellent illustration of pharmacological pleiotropy, detailed with scientific understanding across diverse therapeutic space, animal model validation in every case, and with at least two instances of clinical validation. The story also serves as a good example of the fact that there is much more to successful drug discovery and development beyond accomplishing the already arduous take of clinically proving that a drug is safe, well-tolerated and effective for the pursued indication. Differentiation from existing therapeutics and robust market exclusivity are equally as vital for a program’s success.


   LRIG-Philadelphia Virtual Scientific Meeting March 2021 image

The Pennsylvania Drug Discovery Institute (PDDI) was founded at the Pennsylvania Biotechnology Center of Bucks County in Doylestown, PA in June 2010 by Dr. Allen Reitz and Kathy Czupich as a 501(c) (3) non-profit organization. The current CEO is Dr. Dennis M. Gross.

Its mission is to provide service to the scientific community with workforce reentry assistance for displaced researchers in the pharmaceutical industry, networking activities and supporting and promoting entrepreneurship. In addition, the PDDI has entered into new initiatives in the area of entrepreneurship education and business development engaging the local business and education community.

Help spread the word out about this new forum for Scientists to share their Research and Innovations with the entire LRIG community.   All Laboratory Research and Innovation Group of Philadelphia (LRIG-Philadelphia) events are free and open to all.

If you are interested in presenting or organizing a future event, please send your proposal to Talks.PHL@lrig.org.

Thank you, we'll "see you" on March 3rd

Register Now! on eventbrite.

LRIG Philadelphia 4th Virtual Scientific Meeting

posted Jan 21, 2021, 2:58 PM by Rodney Bednar   [ updated Feb 26, 2021, 12:37 PM ]


https://www.youtube.com/watch?v=H2dGmvLttOY&t=37s


On-Demand Viewing of Event Recording is available for a limited time on LRIG's YouTube Channel.  See: https://www.youtube.com/watch?v=H2dGmvLttOY&t=37s




The 4th Virtual Scientific Meeting is on Wednesday, February 17th, 2021 @ NOON! 

Please encourage your friends and colleagues to register now for this exciting talk.

The Laboratory Research & Innovation Group of Philadelphia (LRIG-Philadelphia) is proud to announce our next Virtual Scientific Meeting. This virtual forum provides an opportunity for Scientists to share their Research & Innovations with the entire LRIG Community.  This ongoing series is free to attend and open to all.

We are excited to hear from Dr. Gyuseok L. Kim from the University of Pennsylvania Singh Center for Nanotechnology on Wednesday, February 17th  at noon EST. 


Further details and required registration is on Eventbritehttps://www.eventbrite.com/e/lrig-philadelphia-virtual-scientific-meeting-feb-2021-tickets-137795938361

About this Event

Nanotechnology and Nanofabrication for Biological Applications

Overview of Presentation:

Principle and examples of key nanofabrication techniques, tool capabilities at the Singh center for nanotechnology at Penn will be presented. Then, microfluidic devices and their concepts and process flow will be introduced to understand the nanofabrication for biological applications.

See below for Information on our speaker and an abstract of her presentation.


Gyuseok L. Kim

Dr. Gyuseok L. Kim is a principal scientist at the Singh Center for Nanotechnology at the University of Pennsylvania. He manages the graduate student fellow program that provides masters students with hands-on processing nanofabrication experience. He also runs educational programs such as Engineering Summer Academy at Penn - Nanofabrication course for high school students. Prior to joining Singh Center, he worked at Samsung Electro-Mechanics as a senior engineer, developed the touch screen panel and characterized devices and materials with electron microscopy. He also worked at Helmholtz-Zentrum Geesthacht in Germany as a research assistant. He received the Ph.D. from Grenoble INP in France, BS and MS both in Material Science and Engineering from Seoul National University in South Korea.

LinkedIn: https://www.linkedin.com/in/gyuseok-kim-b12ab395/

Nanotechnology and Nanofabrication for Biological Applications

Abstract: Nanotechnologies exist around us. Cell phone, tablet, computer, watch and even in Oculus games. Due to the ever increasing need for smaller and faster devices, nanotechnology has been the subject of intense research and commercial activities. The traditional area of nanotechnology includes semiconductors and microelectromechanical system (MEMS) such as diode, transistor, solar cell, quantum dots, actuator and sensor. And most of the nanofabrication process requires lithography, deposition and etch techniques. Recently, non-traditional use of nanotechnology is emerging, especially in biology area. Gradient generator, droplet generator and cell culture device are examples of biological application. In this talk, I will present principle and examples of key nanofabrication techniques, and associated tool capabilities that Singh Center for Nanotechnology at the University of Pennsylvania provides. Then, I will introduce concepts and process flows of actual microfluidic devices to understand the nanofabrication for biological applications.

LRIG Philadelphia 3rd Virtual Scientific Meeting

posted Jan 6, 2021, 5:40 PM by Rodney Bednar   [ updated Jan 26, 2021, 11:34 AM ]

https://youtu.be/3BY4377JgPg


On-Demand Viewing of Event Recording is available for a limited time on LRIG's YouTube Channel.





The 3rd Virtual Scientific Meeting is on Wednesday, January 20th, 2021 @ NOON!  

Please encourage your friends and colleagues to register now for this exciting talk.
REGISTER NOW!


The Laboratory Research & Innovation Group of Philadelphia (LRIG-Philadelphia) is proud to announce our next Virtual Scientific Meeting. This virtual forum provides an opportunity for Scientists to share their Research & Innovations with the entire LRIG Community.  This ongoing series is free to attend and open to all.

We are excited to hear from the GSK's Analytical Automation Specialist, Sharon Matamoros on Wednesday, January 20th at noon EST. 

Further details and required registration is on Eventbrite: https://www.eventbrite.com/e/lrig-philadelphia-virtual-scientific-meeting-jan-2021-tickets-129606810459


About this Event

Automated Platform Analytical Method to Determine Excipient Content in Biopharmaceutical Drug Product using Andrew Alliance Liquid Handler Robot

Overview of Presentation:

The Andrew Alliance liquid handler robot enables automated pipetting, flexible programmable settings, and simple drag and drop protocol designs. This talk describes the automation development challenges and solutions to fully automate a platform analytical method to determine excipient content in monoclonal antibody (mAb) biopharmaceutical drug product.

See below for Information on our speaker and an abstract of her presentation.


Sharon Matamoros

“Sharon Matamoros is an Analytical Automation Specialist in the small molecule High-Throughput Automation Group at the GSK Collegeville site. She has been a member of the team since 2018 and focuses on applying automation to accelerate early-phase drug development. She has a background in Analytical Chemistry”.

LinkedIn: https://www.linkedin.com/in/sharon-matamoros-0a600027/

Automated Platform Analytical Method to Determine Excipient Content in Biopharmaceutical Drug Product using Andrew Alliance Liquid Handler Robot

Sharon Matamoros, GlaxoSmithKline, 1250 South Collegeville Rd, Collegeville, PA 19426

Abstract : The implementation of laboratory automation can accelerate the chemistry, manufacturing, and control activities and build quality into the process. The Andrew Alliance liquid handler robot enables automated pipetting, flexible programmable settings, and simple drag and drop protocol designs. This liquid handler robot is user friendly and ideal for Scientists with limited robotics knowledge. This talk describes the automation development challenges and solutions to fully automate a platform analytical method to determine excipient content in monoclonal antibody (mAb) biopharmaceutical drug product. The automation accomplishes standard solution preparations for a calibration curve, samples with a variety of viscosities, and analytical controls. Analyst vs robot performance is discussed including linearity, precision and accuracy of the results. Automation was successfully implemented in a new laboratory to execute a robust sample preparation protocol.


LRIG Philadelphia 2nd Virtual Scientific Meeting

posted Sep 30, 2020, 12:45 PM by Rodney Bednar   [ updated Dec 6, 2020, 11:52 AM ]

https://www.youtube.com/watch?v=0J2m6RfwDxUOn-Demand Viewing of Event Recording is available for a limited time on LRIG's YouTube Channel.

Virtual WebEx @ Noon on Wednesday Dec 2nd 2020.

Register Now!   

The Laboratory Research & Innovation Group of Philadelphia (LRIG-Philadelphia) is proud to announce the continuation of Virtual Scientific Meetings. This virtual forum provides an opportunity for Scientists to share their Research & Innovations with the entire LRIG Community.  Free to attend, open to all.

We are excited to share LRIG Philadelphia's 2nd Virtual Scientific Meeting is at Noon on Wednesday Dec 2nd.  This lunchtime "WebEx"  event will feature a presentation by a scientists with the U.S. Food and Drug Administration (FDA) and an opportunity for questions and answers.

Further details and required registration is on Eventbritehttps://www.eventbrite.com/e/lrig-philadelphia-virtual-scientific-meeting-tickets-127498173469


Please help us get the word out about this new forum for Scientists to share their Research and Innovations with the entire LRIG community.   All Laboratory Research and Innovation Group of Philadelphia (LRIG-Philadelphia) events are free and open to all interested people.   Please reach out to your colleagues, friends and contacts who may be interested in attending or presenting in a future event.


About this Event

Applications of Biological Target-Based Assays for Chemical Detection.

Although biological target-based assays are commonly used in pharmacology and toxicology, these assays can also be used for chemical detection. In this presentation, the applications, advantages, and limitations of biological target assays for chemical detection will be discussed, and a specific application will be highlighted.  

 

See below for Information on our speakers and an abstract of their presentation.



Michael F. Santillo, Ph.D.


For the past decade I worked as a research scientist at the Center for Food Safety and Applied Nutrition (CFSAN) within the U.S. Food and Drug Administration (FDA). My research at FDA focuses on developing in vitro methods (cellular and biochemical assays) for detecting and predicting the safety of chemicals related to foods and dietary supplements. Additionally, I serve as a FDA’s representative on the assay evaluation team for Tox21, a consortium among several federal agencies who are employing high-throughput screening assays for toxicology testing. I am a member of the American Chemical Society and Society for Laboratory Automation and Screening (SLAS) and served on editorial boards for SLAS Technology and the Journal of Pharmacological and Toxicological Methods. Before joining FDA, I received a Ph.D. in chemistry from Penn State University, where I developed microfluidic devices for cellular assays.


LinkedIn: https://www.linkedin.com/in/mfsantillo


Abstract

Assays that measure interactions between chemicals and their biological targets (receptors, enzymes, ion channels, transporters) play important roles in pharmacological and toxicological research. However, biological target-based assays can also be employed as analytical techniques, where they serve as biosensors for detecting compounds (e.g., drugs, toxins, environmental pollutants) in complex sample matrices. This presentation will provide an overview of the advantages, challenges, and applications of biological target-based assays for chemical detection, especially ones that have been validated and recognized by regulatory agencies or standards organizations (e.g., AOAC International). In addition to providing an overview of these assays, a specific application will be highlighted, where a biological target assay was developed for detecting erectile dysfunction drugs and analogues in tainted products marketed as dietary supplements.



Invite your friends, colleagues, or potentially interested contacts.  Free Registration is Required. Register Here.

LRIG Philly Inaugural Virtual Scientific Meeting

posted Sep 30, 2020, 12:45 PM by Rodney Bednar   [ updated Nov 29, 2020, 10:28 AM ]

https://www.youtube.com/watch?v=V1TrWN0rFQw  On-Demand Viewing of Event Recording is available for a limited time on LRIG's YouTube Channel.

Virtual WebEx @ Noon on Wednesday Oct 7th 2020.

Register Now!   

The Laboratory Research & Innovation Group of Philadelphia (LRIG-Philadelphia) is proud to announce Virtual Scientific Meetings. This virtual forum provides an opportunity for Scientists to share their Research & Innovations with the entire LRIG Community.  Free to attend, open to all.

We are excited to share LRIG Philadelphia's Inaugural Virtual Scientific Meeting is at Noon on Wednesday Oct 7th.  This lunchtime "WebEx"  event will feature an integrated presentation by two GSK scientists and an opportunity for questions and answers.

Further details and required registration is on Eventbrite https://www.eventbrite.com/e/lrig-philadelphia-virtual-scientific-meeting-tickets-122593152419


Please help us get the word out about this new forum for Scientists to share their Research and Innovations with the entire LRIG community.   All Laboratory Research and Innovation Group of Philadelphia (LRIG-Philadelphia) events are free and open to all interested people.   Please reach out to your colleagues, friends and contacts who may be interested in attending or presenting in a future event.


About this Event

Automation Enabled High-Throughput Experimentation for Acceleration of Small Molecule Development

Utilization of laboratory automation can accelerate the chemistry, manufacturing, and control (CMC) activities in pharmaceutical research and development. Automation allows us to accelerate product development by designing, implementing and validating automation protocols that enable high throughput experiments focusing on the characterization of GSK therapeutic candidates.

 

See below for Information on our speakers and an abstract of their presentation.


Sofia Kochiashvili is a Senior Scientist in the small molecule high-throughput automation group at the GSK Collegeville site. She has been a member of the team since 2017 and focuses on applying automation to accelerate early-phase drug development. She has a background in Biology and Chemistry.”

LinkedIn: https://www.linkedin.com/in/sofio-kochiashvili-193a28102


James Thomas is an Investigator in the small molecule high-throughput automation group at the GSK Collegeville site. He has been a member of the team since 2018 and focuses on applying automation to accelerate early-phase drug development. He has a background in Biomedical Engineering and Materials Engineering.”

LinkedIn: https://www.linkedin.com/in/jtdrexel/


Automation Enabled High-Throughput Experimentation for Acceleration of Small Molecule Development

Sofia Kochiashvili and James Thomas; GlaxoSmithKline, 1250 South Collegeville Rd, Collegeville, PA 19426

Utilization of laboratory automation can accelerate the chemistry, manufacturing, and control (CMC) activities in pharmaceutical research and development. Our goal is to accelerate product development by designing, implementing and validating automation protocols that enable high throughput experiments focusing on the characterization of GSK therapeutic candidates. Our automated workflows include crystallization & polymorph screening, formulation development, stability assessment, forced degradation and kinetic solubility studies. The global small molecule automation capabilities include: multi-functional Unchained Labs robotic platforms, Mettler Quantos and Chemspeed solid dispensing platforms, Hamilton, CyBio and Andrew liquid handling systems. These robots enable us to automate sample preparation on a miniaturized scale through liquid and solid dispensing (with integrated balance) combined with heating, cooling, stirring, vortexing and more. The systems are easily programmable, enabling the scientist to customize each experimental design. The platforms interface with analytical instrumentation (eg. HPLC and pH electrodes) to automate data handling by pulling the data from an entire study into a single database. While small molecule automation lab supports workflows ranging from early discovery to phase III clinical trials, we focus on accelerating Pre-CS to FTIH, concomitantly cutting down FTE efforts, money and time. Automation is a growing space with expanding workflow capabilities and collaborations extending outside of the department. Small-molecule automation has supported various departments, completing over 20,000 experiments in 2019.


Invite your friends, colleagues, or potentially interested contacts.  Free Registration is Required. Register Here.

Philly's Annual Vendor Show Rescheduled to June 16, 2022

posted Mar 11, 2020, 11:59 AM by Rodney Bednar   [ updated Jan 24, 2022, 7:39 AM ]

Event Rescheduled for June 16, 2022 Save THAT Date.
FOR VENDOR Registration and INFO SEE: Vendor Show 2022: Exhibitor Information
Thursday October 29, 2020  (4:00 PM to 8:00 PM) 
Philly LRIG Annual Vendor Exhibition 



DoubleTree by Hilton Philadelphia-Valley Forge 
301 West Dekalb Pike, 
King of Prussia, PA 19406 

Google Map Directions
Vendor Exhibition:
  4:00 PM to 8:00 PM
Novel Technologies Presentations:  4:30 PM to 8:00 PM
Free Food: (4:00-7:00) & Dessert (6:00 to 8:00)
Prizes Sponsored by SLAS and LRIG Philly!

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