Chapters‎ > ‎Philadelphia‎ > ‎Events Philly Chapter‎ > ‎

LRIG Philadelphia 6th Virtual Scientific Meeting

posted Apr 3, 2021, 9:08 AM by Rodney Bednar   [ updated Apr 20, 2021, 7:34 PM ]

On-Demand Viewing of Event Recording is available for a limited time on LRIG's YouTube Channel.  

For Direct Video Link:

The 6th Virtual Scientific Meeting is Wednesday, April 7th @ NOON!  

Please encourage your friends and colleagues to register now for this exciting talk.

Register Now on Eventbrite

The Laboratory Research & Innovation Group of Philadelphia (LRIG-Philadelphia) is proud to announce our next Virtual Scientific Meeting. This virtual forum provides an opportunity for Scientists to share their Research & Innovations with the entire LRIG Community.  This ongoing series is free to attend and open to all.

About this Event

This lunchtime "WebEx" event will feature Dual Presentations on High Throughput Cellular Thermal Shift by Scientists at NIH/NCATS and at GSK. There will also be an opportunity for questions and answers.

Overview of Presentations:

High Throughput Cellular Thermal Shift Assays (CETSA): Approaches and Applications

During this webinar, high-throughput cellular thermal shift assays (CETSA) will be discussed. CETSA can be used as a method to detect the engagement of a small molecule with a protein target in cells. High throughput methods and applications will be presented.

Please remember to register and join us for this exciting virtual event. The evening before the event you will receive a link that will allow you to join the WebEx meeting.

See below for information on our speakers and an abstract of their presentations.

   LRIG-Philadelphia Virtual Scientific Meeting April 2021 image

Mark Henderson

Dr. Mark Henderson is a Biology Group Leader in the Early Translation Branch at the National Center for Advancing Translational Sciences (NCATS). His team works on collaborative projects aiming to identify small molecules for disease-relevant targets, focusing on cellular processes that are dysregulated across multiple disorders. He has experience in the design, development, and implementation of high throughput screening assays.


   LRIG-Philadelphia Virtual Scientific Meeting April 2021 image

Lorena Kallal, PhD

Lorena Kallal is a scientist and manager at GlaxoSmithKline in Collegeville, PA. As part of the Screening, Profiling and Mechanistic Biology Department, her team supports programs across the GSK portfolio with cellular assays and experimentation. Lorena has expertise in high throughput screening, phenotypic assays, and drug discovery strategy.


Title: High throughput cellular thermal shift assays (CETSA): approaches and applications.

Mark Henderson, National Center for Advancing Translational Sciences (NCATS), NIH & Lorena Kallal , GlaxoSmithKline, Collegeville, PA

Abstract : The cellular thermal shift assay (CETSA) is a valuable method to assess target engagement within the cellular environment by measuring changes in thermal stability of a protein conferred by ligand binding. The traditional CETSA method is labor intensive, which limits its use when testing large sets of compounds during screening or lead optimization. In recent years, several high-throughput CETSA approaches have been developed to overcome this limitation. During this webinar, we will describe high-throughput CETSA approaches and discuss strengths, pitfalls, and potential applications of these technologies.

Register Now on Eventbrite


Help spread the word out about this new forum for Scientists to share their Research and Innovations with the entire LRIG community.   All Laboratory Research and Innovation Group of Philadelphia (LRIG-Philadelphia) events are free and open to all.

If you are interested in presenting or organizing a future event, please send your proposal to

Thank you, we'll "see you" on April 7th

Register Now on Eventbrite