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LRIG Philadelphia 2nd Virtual Scientific Meeting

posted Sep 30, 2020, 12:45 PM by Rodney Bednar   [ updated Dec 6, 2020, 11:52 AM ] Viewing of Event Recording is available for a limited time on LRIG's YouTube Channel.

Virtual WebEx @ Noon on Wednesday Dec 2nd 2020.

Register Now!   

The Laboratory Research & Innovation Group of Philadelphia (LRIG-Philadelphia) is proud to announce the continuation of Virtual Scientific Meetings. This virtual forum provides an opportunity for Scientists to share their Research & Innovations with the entire LRIG Community.  Free to attend, open to all.

We are excited to share LRIG Philadelphia's 2nd Virtual Scientific Meeting is at Noon on Wednesday Dec 2nd.  This lunchtime "WebEx"  event will feature a presentation by a scientists with the U.S. Food and Drug Administration (FDA) and an opportunity for questions and answers.

Further details and required registration is on Eventbrite

Please help us get the word out about this new forum for Scientists to share their Research and Innovations with the entire LRIG community.   All Laboratory Research and Innovation Group of Philadelphia (LRIG-Philadelphia) events are free and open to all interested people.   Please reach out to your colleagues, friends and contacts who may be interested in attending or presenting in a future event.

About this Event

Applications of Biological Target-Based Assays for Chemical Detection.

Although biological target-based assays are commonly used in pharmacology and toxicology, these assays can also be used for chemical detection. In this presentation, the applications, advantages, and limitations of biological target assays for chemical detection will be discussed, and a specific application will be highlighted.  


See below for Information on our speakers and an abstract of their presentation.

Michael F. Santillo, Ph.D.

For the past decade I worked as a research scientist at the Center for Food Safety and Applied Nutrition (CFSAN) within the U.S. Food and Drug Administration (FDA). My research at FDA focuses on developing in vitro methods (cellular and biochemical assays) for detecting and predicting the safety of chemicals related to foods and dietary supplements. Additionally, I serve as a FDA’s representative on the assay evaluation team for Tox21, a consortium among several federal agencies who are employing high-throughput screening assays for toxicology testing. I am a member of the American Chemical Society and Society for Laboratory Automation and Screening (SLAS) and served on editorial boards for SLAS Technology and the Journal of Pharmacological and Toxicological Methods. Before joining FDA, I received a Ph.D. in chemistry from Penn State University, where I developed microfluidic devices for cellular assays.



Assays that measure interactions between chemicals and their biological targets (receptors, enzymes, ion channels, transporters) play important roles in pharmacological and toxicological research. However, biological target-based assays can also be employed as analytical techniques, where they serve as biosensors for detecting compounds (e.g., drugs, toxins, environmental pollutants) in complex sample matrices. This presentation will provide an overview of the advantages, challenges, and applications of biological target-based assays for chemical detection, especially ones that have been validated and recognized by regulatory agencies or standards organizations (e.g., AOAC International). In addition to providing an overview of these assays, a specific application will be highlighted, where a biological target assay was developed for detecting erectile dysfunction drugs and analogues in tainted products marketed as dietary supplements.

Invite your friends, colleagues, or potentially interested contacts.  Free Registration is Required. Register Here.