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LRIG Philadelphia Inaugural Virtual Scientific Meeting

posted Sep 30, 2020, 12:45 PM by Rodney Bednar   [ updated Oct 19, 2020, 2:18 PM ]

https://www.youtube.com/watch?v=V1TrWN0rFQw  On-Demand Viewing of Event Recording is available for a limited time on LRIG's YouTube Channel.

Virtual WebEx @ Noon on Wednesday Oct 7th 2020.

Register Now!   

The Laboratory Research & Innovation Group of Philadelphia (LRIG-Philadelphia) is proud to announce Virtual Scientific Meetings. This virtual forum provides an opportunity for Scientists to share their Research & Innovations with the entire LRIG Community.  Free to attend, open to all.

We are excited to share LRIG Philadelphia's Inaugural Virtual Scientific Meeting is at Noon on Wednesday Oct 7th.  This lunchtime "WebEx"  event will feature an integrated presentation by two GSK scientists and an opportunity for questions and answers.

Further details and required registration is on Eventbrite https://www.eventbrite.com/e/lrig-philadelphia-virtual-scientific-meeting-tickets-122593152419


Please help us get the word out about this new forum for Scientists to share their Research and Innovations with the entire LRIG community.   All Laboratory Research and Innovation Group of Philadelphia (LRIG-Philadelphia) events are free and open to all interested people.   Please reach out to your colleagues, friends and contacts who may be interested in attending or presenting in a future event.


About this Event

Automation Enabled High-Throughput Experimentation for Acceleration of Small Molecule Development

Utilization of laboratory automation can accelerate the chemistry, manufacturing, and control (CMC) activities in pharmaceutical research and development. Automation allows us to accelerate product development by designing, implementing and validating automation protocols that enable high throughput experiments focusing on the characterization of GSK therapeutic candidates.

 

See below for Information on our speakers and an abstract of their presentation.


Sofia Kochiashvili is a Senior Scientist in the small molecule high-throughput automation group at the GSK Collegeville site. She has been a member of the team since 2017 and focuses on applying automation to accelerate early-phase drug development. She has a background in Biology and Chemistry.”

LinkedIn: https://www.linkedin.com/in/sofio-kochiashvili-193a28102


James Thomas is an Investigator in the small molecule high-throughput automation group at the GSK Collegeville site. He has been a member of the team since 2018 and focuses on applying automation to accelerate early-phase drug development. He has a background in Biomedical Engineering and Materials Engineering.”

LinkedIn: https://www.linkedin.com/in/jtdrexel/


Automation Enabled High-Throughput Experimentation for Acceleration of Small Molecule Development

Sofia Kochiashvili and James Thomas; GlaxoSmithKline, 1250 South Collegeville Rd, Collegeville, PA 19426

Utilization of laboratory automation can accelerate the chemistry, manufacturing, and control (CMC) activities in pharmaceutical research and development. Our goal is to accelerate product development by designing, implementing and validating automation protocols that enable high throughput experiments focusing on the characterization of GSK therapeutic candidates. Our automated workflows include crystallization & polymorph screening, formulation development, stability assessment, forced degradation and kinetic solubility studies. The global small molecule automation capabilities include: multi-functional Unchained Labs robotic platforms, Mettler Quantos and Chemspeed solid dispensing platforms, Hamilton, CyBio and Andrew liquid handling systems. These robots enable us to automate sample preparation on a miniaturized scale through liquid and solid dispensing (with integrated balance) combined with heating, cooling, stirring, vortexing and more. The systems are easily programmable, enabling the scientist to customize each experimental design. The platforms interface with analytical instrumentation (eg. HPLC and pH electrodes) to automate data handling by pulling the data from an entire study into a single database. While small molecule automation lab supports workflows ranging from early discovery to phase III clinical trials, we focus on accelerating Pre-CS to FTIH, concomitantly cutting down FTE efforts, money and time. Automation is a growing space with expanding workflow capabilities and collaborations extending outside of the department. Small-molecule automation has supported various departments, completing over 20,000 experiments in 2019.


Invite your friends, colleagues, or potentially interested contacts.  Free Registration is Required. Register Here.

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